Publications

 2026

Synthesis, crystal structure, Hirshfeld surface and interaction energies analysis of 3-(benzo[d][1,3]dioxol-5-yl)-2-(pyridin-3-yl) thiazolidin-4-one.
Authors: Summara Kousar, Raed Al‑Qawasmeh, Monther Khanfar, Muhammad Saeed
Journal: European Journal of Chemistry 17(2), 99–108
Publication Date: June 30, 2026
DOI: https://doi.org/10.5155/eurjchem.17.2.99-108.2778

Selective Plastic Photo Upcycling to Acetic Acid via Coupled Oxidation and CO₂ Reduction Over an S‑Scheme g‑C₃N₄/Fe₂O₃ Heterojunction
Authors: Zunaira Muhammad, Muhammad Saeed, Senem Çitoğlu, Hatice Duran, Salman Noshear Arshad
Journal: ChemPlusChem 91(4), e202500710
First Published: April 16, 2026
DOI: https://doi.org/10.1002/cplu.202500710

  2025

Thermoselective Synthesis of Drug Intermediates Using Sulphonic Acid Functionalized Heterogeneous Catalysts
Authors: Shahzad Rasheed, Summara Kousar, Muhammad Saeed, Qandeel Almas
Conference: 2025 AIChE Annual Meeting
Publisher: AIChE
Publication Date: November 4, 2025

Probing Solid‑Supported Alkali and Alkaline Earth Metal Salts‑Based Catalysts in the Multicomponent Synthesis of Acridine‑1,8‑diones: Box–Behnken and Density Functional Theory (DFT) Study
Authors: Nisar Ali, Sehrish Sarfaraz, Hina Asif, Minahil Abbas, Mariya Al‑Rashida, Muhammad Saeed, Sobia Rana, Khurshid Ayub, Abdul Hameed
Journal: ChemistrySelect 10(37), e04095
DOI: https://doi.org/10.1002/slct.202504095

Synthesis, mechanistic insights, and anticancer evaluation of novel 2‑aroylbenzo[b]thiophen‑3‑ols: A DFT and Hirshfeld surface analysis
Authors: Asma Mukhtar, Ali Iftikhar, Maria Maqbool, Amir Faisal, Khurshid Ayub, Sammer Yousuf, Muhammad Saeed
Journal: Journal of Molecular Structure 1324, 140802
DOI: https://doi.org/10.1016/j.molstruc.2024.140802

 2024


Fabrication of CuWO₄@MIL‑101 (Fe) nanocomposite for efficient OER and photodegradation of methylene blue
Authors: Mariam Khan, M.M. Ahmed, M.N. Akhtar, M. Sajid, N.N. Riaz, M. Asif, M. Kashif, … Muhammad Saeed
Journal: Heliyon 10(23)
Publication Year: 2024
DOI:https://doi.org/10.1016/j.heliyon.2024.e40546

Optimization study and application of Box–Behnken model for probing eggshell supported transition metals based catalysts to synthesize hydrazone & dihydropyrimidinones
Authors: Rabia Perveen, F. Latif, M. Abbas, K. Ayub, S. Sarfaraz, Muhammad Saeed, S. Rana, …
Journal: Scientific Reports 14(1), 23270
DOI: https://doi.org/10.1038/s41598-024-74876-6

Synthesis of 3‑methyl‑N‑((4′-(3‑methylbenzamido)‑[1,1′‑biphenyl]‑4‑yl) carbamothioyl) benzamide: X‑ray structural analysis, DFT‑guided investigation, Hirshfeld analysis
Authors: Faiza Younas, A. Saeed, T. Hökelek, C. Schulzke, S. Tahira, B.J. Elvers, Muhammad Saeed
Journal: Journal of Molecular Structure 1311, 138399
DOI:https://doi.org/10.1016/j.molstruc.2024.138399

Iron‑catalysed C–H ortho‑arylation of edaravone, a promising monoamine oxidase‑B inhibitor
Authors: Soneela Asghar, Mattia Manzotti, Alexander Atkins, S. Tailor, H.A. Sparkes, Muhammad Saeed, …
Journal: Tetrahedron 158, 133983
DOI:https://doi.org/10.1016/j.tet.2024.133983

Facile synthesis of substituted 2‑aroylbenzo[b]thiophen‑3‑ols to form novel triazole hybrids using click chemistry
Authors: Asma Mukhtar, Arif Hussain, Faiza Younas, Sammer Yousuf, Muhammad Saeed
Journal: RSC Advances 14(15), 10270–10279
DOI: https://doi.org/10.1039/d4ra01146e


2023

Part‑II: An update of Schiff bases synthesis and applications in medicinal chemistry – a patent review (2016–2023)
Authors: Hafiza Amna Younus, Farwa Saleem, A. Hameed, Mariya Al‑Rashida, Raed Al‑Qawasmeh, … Muhammad Saeed
Journal: Expert Opinion on Therapeutic Patents 33(12), 841–864


Repurposing of investigational cancer drugs: Early phase discovery of dengue virus NS2B/NS3 protease inhibitors
Authors: Hafiza Nosheen Saleem, Summara Kousar, A.H. Jiskani, I. Sohail, Amir Faisal, Muhammad Saeed
Journal: Archiv der Pharmazie e2300292
DOI:https://doi.org/10.1002/ardp.20230029
2

The photocatalytic and antibacterial potential of highly efficient S‑scheme binary S‑gC₃N₄@Co‑zinc ferrite nanocomposite
Authors: Syeda Saba Hassan, M. Javed, M.N. Akhtar, M.A. Qamar, N. Ahmed, Muhammad Saeed, …
Journal: Optical Materials 142, 114046
DOI:https://doi.org/10.1016/j.optmat.2023.114046

Plasma‑based ozonolysis of lignin waste materials for the production of value‑added chemicals
Authors: Rabia Muazzam, A. Hafeez, M. Uroos, Muhammad Saeed, F. Rehman, N. Muhammad
Journal: Biomass Conversion and Biorefinery 13, 5903–5919
DOI: https://doi.org/10.1007/s13399-021-01707-3

Exploring chromone sulfonamides and sulfonylhydrazones as highly selective ectonucleotidase inhibitors: synthesis, biological evaluation and in silico study
Authors: Hafiza Amna Younus, Muhammad Saeed, A. Mahmood, M.S.K. Jadoon, A. Hameed, A. Asari, …
Journal: Bioorganic Chemistry 134, 106450
DOI:https://doi.org/10.1016/j.bioorg.2023.106450


2022

Endophytic bacteria of Fagonia indica Burm. f revealed to harbour rich secondary antibacterial metabolites
Authors: Lubna Rahman, Asma Mukhtar, S. Ahmad, L. Rahman, M. Ali, Muhammad Saeed, Z.K. Shinwari
Journal: PLOS ONE 17(12), e0277825
DOI:https://doi.org/10.1371/journal.pone.0277825

Synthesis, X‑Ray crystallography and HF/DFT analysis of N‑(diethylcarbamothioyl) furan‑2‑carboxamide, analyzed by experimental and theoretical methods
Authors: A. Saeed, S. Ashraf, G. Shabir, T. Hökelek, U. Flörke, Asma Mukhtar, Muhammad Saeed
Journal: Journal of Molecular Structure 1268, 133721
DOI:https://doi.org/10.1016/j.molstruc.2022.133721

Novel carboxylic acid‑capped silver nanoparticles as antimicrobial and colorimetric sensing agents
Authors: Muhammad Imran Irfan, F. Amjad, A. Abbas, M.F.U. Rehman, F. Kanwal, Muhammad Saeed, S. Ullah, …
Journal: Molecules 27(11), 3363
DOI:https://doi.org/10.3390/molecules27113363

Synthetic flavonoids as potential antiviral agents against SARS‑CoV‑2 main protease
Authors: Farwa Batool, Ehsan Ullah Mughal, K. Zia, A. Sadiq, N. Naeem, A. Javid, Z. Ul‑Haq, … Muhammad Saeed
Journal: Journal of Biomolecular Structure and Dynamics 40(8), 3777–3788
DOI:https://doi.org/10.1080/07391102.2022.2045678

Postharvest shelf life enhancement of peach fruit treated with glucose oxidase immobilized on ZnO nanoparticles
Authors: Razia Batool, S.A.R. Kazmi, S. Khurshid, Muhammad Saeed, S. Ali, A. Adnan, F. Altaf, …
Journal: Food Chemistry 366, 130591
DOI:https://doi.org/10.1016/j.foodchem.2021.130591

2021

Minocycline Derived Silver Nanoparticles for Assessment of Their Antidiabetic Potential against Alloxan induced Diabetic Mice
Authors: Syed Akif Raza Kazmi, M.Z. Qureshi, S.S. Alhewairini, S. Ali, S. Khurshid, Muhammad Saeed, …
Journal: Pharmaceutics 13(10), 1678
DOI:https://doi.org/10.3390/pharmaceutics13101678

Catalytic C–O bond cleavage in a β‑O‑4 lignin model through intermolecular hydrogen transfer
Authors: Muhammad Ahsan Usman, M. Naeem, Muhammad Saeed, M. Zaheer
Journal: Inorganica Chimica Acta 521, 120305
DOI:https://doi.org/10.1016/j.ica.2021.120305

Facile Synthesis and In Vitro Activity of N‑Substituted 1,2‑Benzisothiazol‑3(2H)‑ones against Dengue Virus NS2BNS3 Protease
Authors: Farwa Batool, Muhammad Saeed, Hafiza Nosheen Saleem, L. Kirschner, J. Bodem
Journal: Pathogens 10(4), 464
DOI:https://doi.org/10.3390/pathogens10040464

Schiff‑based metal complexes of lamotrigine: design, synthesis, characterization, and biological evaluation
Authors: Saima Najm, Humaira Naureen, K. Sultana, F. Anwar, M.M. Khan, H. Nadeem, Muhammad Saeed
Journal: ACS Omega 6(11), 7719
DOI:https://doi.org/10.1021/acsomega.1c00027
         
2020

Sulfonylhydrazones: Design, synthesis and investigation of ectonucleotidase (ALP & e5′ NT) inhibition activities
Authors: Hafiza Amna Younus, A. Hameed, A. Mahmood, M.S. Khan, Muhammad Saeed, Farwa Batool, …
Journal: Bioorganic Chemistry 100, 103827
DOI:https://doi.org/10.1016/j.bioorg.2020.103827

Synthesis and evaluation of novel S‑benzyl‑ and S‑alkylphthalimide‑oxadiazole‑benzenesulfonamide hybrids as inhibitors of dengue virus protease
Authors: Syeda Shamila Hamdani, B.A. Khan, S. Hameed, Farwa Batool, Hafiza Nosheen Saleem, E.U. Mughal, … Muhammad Saeed
Journal: Bioorganic Chemistry 96, 103567
DOI:https://doi.org/10.1016/j.bioorg.2020.103567

Treatment of HCV Genotype‑1a Infection with Sofosbuvir/Daclatasvir in a Child Suffering from Thalassemia‑Major
Authors: Hafiz Javed Mansoor, M.S. Walayt, H. Ahmed, M.A. Khan, Muhammad Saeed
Journal: RADS Journal of Pharmacy and Pharmaceutical Sciences 8(3), 168–172

 2019

Inhibition of Dengue Virus Protease by Eugeniin, Isobiflorin, and Biflorin Isolated from the Flower Buds of Syzygium aromaticum (Cloves)
Authors: Hafiza Nosheen Saleem, Farwa Batool, Hafiz Javed Mansoor, S. Shahzad‑ul‑Hussan, Muhammad Saeed
Journal: ACS Omega 4(1), 1525–1533
DOI:https://doi.org/10.1021/acsomega.8b02861

Kerr Nonlinearity in germanium selenide nanoflakes measured by Z‑scan and spatial self‑phase modulation techniques
Authors: Yue Jia, Muhammad Saeed, …
Journal: Optics Express 27, 20857
DOI: https://doi.org/10.1364/OE.27.020857

2018

Potential targets for therapeutic intervention and structure‑based vaccine design against Zika virus
Authors: Amina Qadir, M. Riaz, Muhammad Saeed, S. Shahzad‑ul‑Hussan
Journal: European Journal of Medicinal Chemistry 156, 444–460
DOI:https://doi.org/10.1016/j.ejmech.2018.07.014
                        
 2017

Deciphering the Resistance Profile of Cancerous Thymidylate Synthase
Authors: Z. Islam, I. Gurevic, Muhammad Saeed, S. Rasool, Amnon Kohen
Journal: FASEB Journal 31, 921.12


Synthesis of lignin model compound containing a β‑O‑4 linkage
Authors: Asma Mukhtar, M. Zaheer, Muhammad Saeed, W. Voelter
Journal: Zeitschrift für Naturforschung B 72(2), 119–124
DOI: https://doi.org/10.1515/znb-2016-0201  

 2015


Targeting the de novo Biosynthesis of Thymidylate for PET Probe Development in Pancreatic Cancer Imaging
Authors: Thushani D. Nilaweera, Muhammad Saeed, Amnon Kohen
Journal: Biochemistry 54(5), 1287–1295
Year: 2015
DOI: https://doi.org/10.1021/bi501481n

2012

A fast chemoenzymatic synthesis of [¹¹C]‑N⁵,N¹⁰‑methylenetetrahydrofolate as a potential PET tracer for proliferating cells Authors: Muhammad Saeed, Timothy J. Tewson, Colbin E. Erdahl, Amnon Kohen Journal: Nuclear Medicine and Biology 39(5), 697–701
Publication Date: July 15, 2012
DOI:https://doi.org/10.1016/j.nucmedbio.2011.12.003

A fast chemoenzymatic synthesis of [11C]‑N5,N10‑methylenetetrahydrofolate as a potential PET tracer for proliferating cells
Authors: Muhammad Saeed, T.J. Tewson, C.E. Erdahl, Amnon Kohen
Journal: Nuclear Medicine and Biology 39(5), 697–701
DOI:https://doi.org/10.1016/j.nucmedbio.2011.12.003

Effect of tumour necrosis factor‑alpha on estrogen metabolic pathways in breast cancer cells
Authors: M. Kamel, S. Shouman, M. El‑Merzebany, G. Kilic, T. Veenstra, Muhammad Saeed, …
Journal: Journal of Cancer 3, 310–319


Mechanism of DNA depurination by carcinogens in relation to cancer initiation
Authors: Ercole Cavalieri, Muhammad Saeed, M. Zahid, D. Cassada, D. Snow, M. Miljkovic, …
Journal: IUBMB Life 64(2), 169–179
DOI: https://doi.org/10.1002/iub.58

 2011

Formation of dopamine quinone‑DNA adducts and their potential role in the etiology of Parkinson’s disease
Authors: M. Zahid, Muhammad Saeed, L. Yang, C. Beseler, E. Rogan, E.L. Cavalieri
Journal: IUBMB Life 63(12), 1087–1093
DOI: https://doi.org/10.1002/iub.538

Formation of diethylstilbestrol–DNA adducts in human breast epithelial cells and inhibition by resveratrol
Authors: B. Hinrichs, M. Zahid, Muhammad Saeed, M.F. Ali, E.L. Cavalieri, E.G. Rogan
Journal: Journal of Steroid Biochemistry and Molecular Biology 127(3–5), 276–281
DOI: https://doi.org/10.1016/j.jsbmb.2011.03.012 (doi.org in Bing)

Novel positron emission tomography tracer distinguishes normal from cancerous cells
Authors: Muhammad Saeed, D. Sheff, Amnon Kohen
Journal: Journal of Biological Chemistry 286(39), 33872–33878
DOI: https://doi.org/10.1074/jbc.M111.275446

The effect of tamoxifen and raloxifene on estrogen metabolism and endometrial cancer risk
Authors: M.Y. Williams‑Brown, S.M. Salih, X. Xu, T.D. Veenstra, Muhammad Saeed, S.K. Theiler, …
Journal: Journal of Steroid Biochemistry and Molecular Biology 126(3–5), 78–86
DOI:https://doi.org/10.1016/j.jsbmb.2011.03.010

Resveratrol and N‑acetylcysteine block the cancer‑initiating step in MCF‑10F cells
Authors: M. Zahid, Muhammad Saeed, C. Beseler, E.G. Rogan, E.L. Cavalieri
Journal: Free Radical Biology and Medicine 50(1), 78–85
DOI: https://doi.org/10.1016/j.freeradbiomed.2010.10.701