{"id":55,"date":"2026-07-14T20:40:26","date_gmt":"2026-07-14T20:40:26","guid":{"rendered":"https:\/\/medchem.lums.edu.pk\/index.php\/penny-grow-about-us\/"},"modified":"2026-07-17T20:14:46","modified_gmt":"2026-07-17T20:14:46","slug":"penny-grow-about-us","status":"publish","type":"page","link":"https:\/\/medchem.lums.edu.pk\/?page_id=55","title":{"rendered":"Penny Grow About us"},"content":{"rendered":"\t\t
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About Us<\/h1>\t\t\t\t<\/div>\n\t\t\t\t
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The Bioorganic & Medicinal Chemistry (BMC) group is committed to advancing science at the interface of chemistry and biology. Our research focuses on organic synthesis, computational chemistry, molecular modeling, and biological evaluation to discover new therapeutic agents and smart drug delivery platforms. We explore areas such as anticancer and antiviral drug discovery, endocrine\u2011resistant breast cancer, peptide\u2011based nanomaterials, and sustainable catalytic technologies. Through interdisciplinary training and international collaborations, we aim to bridge fundamental chemistry with translational biomedical research, empowering the next generation of scientists.<\/p>\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tBack to home<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t
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Publications
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*2026<\/strong>

1- Synthesis, crystal structure, Hirshfeld surface and interaction energies analysis of 3-(benzo[d][1,3]dioxol-5-yl)-2-(pyridin-3-yl)thiazolidin-4-one<\/strong> Authors: Summara Kousar, Raed Al\u2011Qawasmeh, Monther Khanfar, Muhammad Saeed<\/em>
European Journal of Chemistry<\/em>
DOI: https:\/\/doi.org\/10.5155\/eurjchem.17.2.99-108.2778<\/a>

2- Selective Plastic Photo Upcycling to Acetic Acid via Coupled Oxidation and CO\u2082 Reduction Over an S\u2011Scheme g\u2011C\u2083N\u2084\/Fe\u2082O\u2083 Heterojunction<\/strong> Authors: Zunaira Muhammad, Muhammad Saeed, Senem \u00c7ito\u011flu, Hatice Duran, Salman Noshear Arshad<\/em> ChemPlusChem<\/em> DOI: https:\/\/doi.org\/10.1002\/cplu.202500710<\/a>

*2025 <\/strong>

3- Thermoselective Synthesis of Drug Intermediates Using Sulphonic Acid Functionalized Heterogeneous Catalysts<\/strong>
Authors: Shahzad Rasheed, Summara Kousar, Muhammad Saeed, Qandeel Almas<\/em>
Presented at the 2025 AIChE Annual Meeting (Conference abstract \u2013 DOI not assigned)<\/em>

4- Probing Solid\u2011Supported Alkali and Alkaline Earth Metal Salts\u2011Based Catalysts in the Multicomponent Synthesis of Acridine\u20111,8\u2011diones: Box\u2013Behnken and Density Functional Theory (DFT) Study<\/strong> Authors: Nisar Ali, Sehrish Sarfaraz, Hina Asif, Minahil Abbas, Mariya Al\u2011Rashida, Muhammad Saeed, Sobia Rana, Khurshid Ayub, Abdul Hameed<\/em> ChemistrySelect<\/em>
DOI:https:\/\/doi.org\/10.1002\/slct.202504095<\/a>

5- Probing Solid\u2011Supported Alkali and Alkaline Earth Metal Salts\u2011Based Catalysts in the Multicomponent Synthesis of Acridine\u20111,8\u2011diones: Box\u2013Behnken and Density Functional Theory (DFT) Study<\/strong>
Authors: Nisar Ali, Sehrish Sarfaraz, Hina Asif, Minahil Abbas, Mariya Al\u2011Rashida, Muhammad Saeed, Sobia Rana, Khurshid Ayub, Abdul Hameed<\/em> ChemistrySelect<\/em>
DOI:https:\/\/doi.org\/10.1002\/slct.202504095<\/a>
*2024

6- Fabrication of CuWO\u2084@MIL\u2011101 (Fe) nanocomposite for efficient OER and photodegradation of methylene blue<\/strong>
Authors: Mariam Khan, Muhammad Mahboob Ahmed, Muhammad Nadeem Akhtar, Muhammad Sajid, Nagina Naveed Riaz, Muhammad Asif, Muhammad Kashif, Bushra Shabbir, Khalil Ahmad, Muhammad Saeed, Maryam Shafiq, Tayyaba Shabir<\/em>
Heliyon, December 15, 2024<\/em>

7- Optimization study and application of Box\u2013Behnken model for probing eggshell supported transition metals based catalysts to synthesize hydrazone & dihydropyrimidinones<\/strong> Authors: Rabia Perveen, Fiza Latif, Minahil Abbas, Khurshid Ayub, Sehrish Sarfaraz, Muhammad Saeed, Sobia Rana, Mariya Al\u2011Rashida, Muhammad Asif Nawaz, Abdul Hameed<\/em> Scientific Reports<\/em>

8- Synthesis of 3\u2011methyl\u2011N\u2011((4\u2032\u2011(3\u2011methylbenzamido)\u2011[1,1\u2032\u2011biphenyl]\u20114\u2011yl)carbamothioyl)benzamide, X\u2011ray structural analysis, DFT\u2011guided investigation, Hirshfeld analysis and docking to jack bean urease<\/strong> Authors: Faiza Younas, Aamer Saeed, Tuncer H\u00f6kelek, Carola Schulzke, Sarwat Tahira, Benedict J. Elvers, Muhammad Saeed<\/em>
Journal of Molecular Structure<\/em>
DOI:https:\/\/doi.org\/10.1016\/j.molstruc.2024.138399

9- Iron\u2011catalysed C\u2013H ortho\u2011arylation of edaravone, a promising monoamine oxidase\u2011B inhibitor<\/strong> Authors: Soneela Asghar, Mattia Manzotti, Alexander Atkins, Sanita Tailor, Hazel A. Sparkes, Muhammad Saeed, Robin B. Bedford<\/em> Tetrahedron, April 18, 2024<\/em> DOI: https:\/\/doi.org\/10.1016\/j.tet.2024.133983<\/a>

10- Facile synthesis of substituted 2\u2011aroylbenzo[b]thiophen\u20113\u2011ols to form novel triazole hybrids using click chemistry<\/strong> Authors: Asma Mukhtar, Arif Hussain, Faiza Younas, Sammer Yousuf, Muhammad Saeed<\/em> RSC Advances, March 28, 2024<\/em>
DOI: https:\/\/doi.org\/10.1039\/d4ra01146e<\/a>
*2023<\/strong>

11- Part\u2011II: An update of Schiff bases synthesis and applications in medicinal chemistry \u2013 a patent review (2016\u20132023)<\/strong> Authors: Hafiza Amna Younus, Faiza Saleem, Abdul Hameed, Mariya Al\u2011Rashida, Raed A. Al\u2011Qawasmeh, Mohamed El\u2011Naggar, Sobia Rana, Muhammad Saeed, Khalid Mohammed Khan<\/em> Expert Opinion on Therapeutic Patents, December 2, 2023<\/em> DOI:https:\/\/doi.org\/10.1080\/13543776.2023.2297729<\/a>

12- Repurposing of investigational cancer drugs: Early phase discovery of dengue virus NS2B\/NS3 protease inhibitors<\/strong> Authors: Hafiza N. Saleem, Summara Kousar, Ammar Hassan Jiskani, Iqra Sohail, Amir Faisal, Muhammad Saeed<\/em> Archiv der Pharmazie, August 15, 2023<\/em> DOI: https:\/\/doi.org\/10.1002\/ardp.202300292<\/a>

13- The photocatalytic and antibacterial potential of highly efficient S\u2011scheme binary S\u2011gC\u2083N\u2084@Co\u2011zinc ferrite nanocomposite<\/strong> Authors: Syeda Saba Hassan, Mohsin Javed, Muhammad Nadeem Akhtar, Muhammad Azam Qamar, Naveed Ahmed, Muhammad Saeed, Komal Aroosh, Saira Khan, Samia Asif<\/em>
Optical Materials, August 1, 2023<\/em>
DOI:https:\/\/doi.org\/10.1016\/j.optmat.2023.114046<\/a>

14- Plasma\u2011based ozonolysis of lignin waste materials for the production of value\u2011added chemicals<\/strong> Authors: Rabia Muazzam, Ainy Hafeez, Maliha Uroos, Muhammad Saeed, Fahad Rehman, Nawshad Muhammad<\/em> Biomass Conversion and Biorefinery, May 13, 2023<\/em> DOI: https:\/\/doi.org\/10.1007\/s13399-021-01707-3<\/a>

15- Exploring chromone sulfonamides and sulfonylhydrazones as highly selective ectonucleotidase inhibitors: synthesis, biological evaluation and in silico study<\/strong>
Authors: Hafiza Amna Younus, Muhammad Saeed, Abid Mahmood, Muhammad Siraj Khan Jadoon, Abdul Hameed, Asnuzilawati Asari, Habsah Mohamad, Julie Pelletier, Jean S\u00e9vigny, Jamshed Iqbal, Mariya Al\u2011Rashida<\/em>
Bioorganic Chemistry, May 1, 2023<\/em>

Publications \u2013 2022<\/strong>

16- Endophytic bacteria of Fagonia indica<\/em> Burm. f revealed to harbour rich secondary antibacterial metabolites<\/strong>
Authors: Lubna Rahman, Asma Mukhtar, Sajjad Ahmad, Lutfur Rahman, Muhammad Ali, Muhammad Saeed, Zabta Khan Shinwari<\/em>
PLOS ONE, December 15, 2022<\/em>

17- <\/em>Synthesis, X\u2011Ray crystallography and HF\/DFT analysis of N\u2011(diethylcarbamothioyl) furan\u20112\u2011carboxamide, analyzed by experimental and theoretical methods<\/strong>
Authors: Aamer Saeed, Saba Ashraf, Ghulam Shabir, Tuncer H\u00f6kelek, Ulrich Fl\u00f6rke, Asma Mukhtar, Muhammad Saeed<\/em>
Journal of Molecular Structure, November 15, 2022<\/em>

18- <\/em>Novel carboxylic acid\u2011capped silver nanoparticles as antimicrobial and colorimetric sensing agents<\/strong>
Authors: Muhammad Imran Irfan, Fareeha Amjad, Azhar Abbas, Muhammad Fayyaz Ur Rehman, Fariha Kanwal, Muhammad Saeed, Sami Ullah, Changrui Lu<\/em>
Molecules, May 24, 2022<\/em>
DOI:https:\/\/doi.org\/10.3390\/molecules27113363

19- Synthetic flavonoids as potential antiviral agents against SARS\u2011CoV\u20112 main protease<\/strong>
Authors: Farwa Batool, Ehsan Ullah Mughal, Komal Zia, Amina Sadiq, Nafeesa Naeem, Asif Javid, Zaheer Ul\u2011Haq, Muhammad Saeed<\/em>
Journal of Biomolecular Structure and Dynamics, May 24, 2022<\/em>
DOI: https:\/\/doi.org\/10.1080\/07391102.2022.2045678

20- Postharvest shelf life enhancement of peach fruit treated with glucose oxidase immobilized on ZnO nanoparticles<\/strong>
Authors: Razia Batool, Syed Akif Raza Kazmi, Shazia Khurshid, Muhammad Saeed, Sikandar Ali, Ahmad Adnan, Faizah Altaf, Aminah Hameed, Farwa Batool, Noor Fatima<\/em>
Food Chemistry, January 1, 2022<\/em>
DOI:https:\/\/doi.org\/10.1016\/j.foodchem.2021.130591
Publications \u2013 2021

21- Minocycline Derived Silver Nanoparticles for Assessment of Their Antidiabetic Potential against Alloxan induced Diabetic Mice<\/strong>
Authors: Syed Akif Raza Kazmi, Muhammad Zahid Qureshi, Saleh S. Alhewairini, Shaukat Ali, Shazia Khurshid, Muhammad Saeed, Shumaila Mumtaz, Tafail Akbar Mughal<\/em>
Pharmaceutics, June 1, 2021<\/em>
DOI:https:\/\/doi.org\/10.3390\/pharmaceutics13101678


22- Catalytic C\u2013O bond cleavage in a \u03b2\u2011O\u20114 lignin model through intermolecular hydrogen transfer<\/strong>
Authors: Muhammad Ahsan Usman, Maham Naeem, Muhammad Saeed, Muhammad Zaheer<\/em>
Inorganica Chimica Acta, June 1, 2021<\/em>
DOI: 10.1016\/j.ica.2021.120305<\/strong>

23- <\/em>Facile Synthesis and In Vitro Activity of N\u2011Substituted 1,2\u2011Benzisothiazol\u20113(2H)\u2011ones against Dengue Virus NS2BNS3 Protease<\/strong>
Authors: Farwa Batool, Muhammad Saeed, Hafiza Nosheen Saleem, Luisa Kirschner, Jochen Bodem<\/em>
Pathogens, April 12, 2021<\/em>
DOI: 10.3390\/pathogens10040464<\/strong>

24- <\/em>Organizational flexibility and project portfolio performance: the roles of innovation, absorptive capacity and environmental dynamism<\/strong>
Authors: Muhammad Aamir Saeed, Yuanyuan Jiao, Muhammad Mohsin Zahid, Humaira Tabassum, Shazia Nauman<\/em>
International Journal of Managing Projects in Business, April 6, 2021<\/em>
DOI: 10.1108\/IJMPB-02-2020-0058<\/strong>

25- <\/em>Schiff\u2011based metal complexes of lamotrigine: design, synthesis, characterization, and biological evaluation<\/strong>
Authors: Saima Najm, Humaira Naureen, Kishwar Sultana, Fareeha Anwar, Muhammad Mubbashir Khan, Humaira Nadeem, Muhammad Saeed<\/em>
ACS Omega, March 15, 2021<\/em>Publications \u2013 2020
DOI: 10.1021\/acsomega.1c00027<\/strong>

26- Sulfonylhydrazones: Design, synthesis and investigation of ectonucleotidase (ALP & e5\u2032 NT) inhibition activities<\/strong>
Authors: Hafiza Amna Younus, Abdul Hameed, Abid Mahmood, Muhammad Siraj Khan, Muhammad Saeed, Farwa Batool, Asnuzilawati Asari, Habsah Mohamad, Julie Pelletier, Jean S\u00e9vigny, Jamshed Iqbal, Mariya Al\u2011Rashida<\/em>
Bioorganic Chemistry, July 1, 2020<\/em>
DOI: 10.1016\/j.bioorg.2020.103827<\/strong>

27- <\/em>The South Asian Health Foundation (UK) guidelines for managing diabetes during Ramadan<\/strong>
Authors: W Hanif, V Patel, SN Ali, A Karamat, M Saeed, M Hassanein, A Syed, TA Chowdhury, A Farooqi, K Khunti<\/em>
Diabetes Research and Clinical Practice, June 1, 2020<\/em>
DOI: 10.1016\/j.diabres.2020.108145<\/strong>

28- <\/em>Synthesis and evaluation of novel S\u2011benzyl\u2011 and S\u2011alkylphthalimide\u2011oxadiazole\u2011benzenesulfonamide hybrids as inhibitors of dengue virus protease<\/strong>
Authors: Syeda Shamila Hamdani, Bilal Ahmad Khan, Shahid Hameed, Farwa Batool, Hafiza Nosheen Saleem, Ehsan Ullah Mughal, Muhammad Saeed<\/em>
Bioorganic Chemistry, March 1, 2020<\/em>
DOI: 10.1016\/j.bioorg.2020.103567<\/strong>

29- <\/em>The Antidiabetic Effect of Cinnanomum zeylenicum<\/em> (Girfa) Aqueous Extract on Induced Diabetic Albino Rats<\/strong>
Authors: MH Saeed, SMA Bakhit, LE Taha<\/em>
Diabetes, 2020<\/em>


30 <\/em>Treatment of HCV Genotype\u20111a Infection with Sofosbuvir\/Daclatasvir in a Child Suffering from Thalassemia\u2011Major<\/strong>
Authors: Hafiz Javed Mansoor, Muhammad Salman Walayt, Hammad Ahmed, Mahtab Ahmad Khan, Muhammad Saeed<\/em>
RADS Journal of Pharmacy and Pharmaceutical Sciences, 2020<\/em>
Publications \u2013 2019

31- Symplasmic phloem unloading and radial post\u2011phloem transport via vascular rays in tuberous roots of Manihot esculenta<\/em><\/strong>
Rabih Mehdi, Christian E Lamm, Ravi Bodampalli Anjanappa, Christina M\u00fcdsam, Muhammad Saeed, Janine Klima, Max E Kraner, Frank Ludewig, Michael Knoblauch, Wilhelm Gruissem, Uwe Sonnewald, Wolfgang Zierer<\/em>
Journal of Experimental Botany, October 15, 2019<\/em>
DOI: 10.1093\/jxb\/erz297<\/strong>

32- <\/em>Kerr Nonlinearity in germanium selenide nanoflakes measured by Z\u2011scan and spatial self\u2011phase modulation techniques and its applications in all\u2011optical information conversion<\/strong>
Yue Jia, Zhongfu Li, Muhammad Saeed, Jie Tang, Houzhi Cai, Yuanjiang Xiang<\/em>
Optics Express, July 11, 2019<\/em>
DOI: 10.1364\/OE.27.020857<\/strong>

33-<\/em>Inhibition of Dengue virus protease by chemical constituents of a clove: From food ingredient to medicine<\/strong>
Muhammad Saeed<\/em>
Conference Abstracts, American Chemical Society, March 31, 2019<\/em>
DOI: 10.1021\/acsomega.8b02861<\/strong>

34- <\/em>Inhibition of Dengue Virus Protease by Eugeniin, Isobiflorin, and Biflorin Isolated from the Flower Buds of Syzygium aromaticum<\/em> (Cloves)<\/strong>
Hafiza Nosheen Saleem, Farwa Batool, Hafiz Javed Mansoor, Syed Shahzad\u2011ul\u2011Hussan, Muhammad Saeed<\/em>
ACS Omega, January 17, 2019<\/em>Publications \u2013 2018

35- A brief review on plant growth promoting rhizobacteria (PGPR): a key role in plant growth promotion<\/strong>
Umair Mehmood, Muhammad Inam\u2011ul\u2011Haq, Muhammad Saeed, Adeela Altaf, Farooq Azam, Sikandar Hayat<\/em>
Plant Protection, September 11, 201836<\/em>
DOI: 10.3389\/fpls.2018.01473<\/strong>


36- <\/em>Potential targets for therapeutic intervention and structure\u2011based vaccine design against Zika virus<\/strong>
Amina Qadir, Muhammad Riaz, Muhammad Saeed, Syed Shahzad\u2011ul\u2011Hussan<\/em>
European Journal of Medicinal Chemistry, August 5, 2018<\/em>
DOI: 10.1016\/j.ejmech.2018.07.014<\/strong>

37- <\/em>High rates of non\u2011adherence to antidiabetic, antihypertensive and lipid\u2011lowering treatment in patients with Type 2 diabetes revealed by LC\u2011MS\/MS<\/strong>
Ali Abdulnabi Suwaidan, P Gupta, P Patel, A Burns, M Saeed, D Lane, S Seidu, K Khunti<\/em>
European Heart Journal, August 1, 2018<\/em>
DOI: 10.1093\/eurheartj\/ehy566.P6187<\/strong>

38- <\/em>Superstructure manipulation and electronic measurement of monolayers comprising discotic liquid crystals with intrinsic dipole moment using STM\/STS<\/strong>
Kum\u2011Yi Cheng, Chih\u2011Hsun Lin, Mei\u2011Chun Tzeng, Ayyaz Mahmood, Muhammad Saeed, Chun\u2011hsien Chen, Chi Wi Ong, Shern\u2011Long Lee<\/em>
Chemical Communications, 2018<\/em>
DOI: 10.1039\/C8CC04241A<\/strong>

39- <\/em>A preliminary list of hover flies (Diptera: Syrphidae) with new locality records from Swat, Khyber Pakhtunkhwa, Northern Pakistan<\/strong>
M Saeed, MA Hassan, I Mastoi, A Arshad<\/em>
Journal of Entomology and Zoology Studies, 2018<\/em>Publications \u2013 2017

40- Species diversity and ethnobotanical study of Allai valley in the western Himalayan region of Pakistan<\/strong>
Muhammad Abbas Khan, Shah Masaud Khan, Shujaul Mulk Khan, Ijaz Hussain, Sher Aslam Khan, Muhammad Liaqat, Muhammad Saeed, Sardar Ali<\/em>
Pakistan Journal of Weed Science Research, June 1, 2017<\/em>
DOI: 10.28941\/pjwsr.v23i2.207-220<\/strong>

41- <\/em>Deciphering the Resistance Profile of Cancerous Thymidylate Synthase<\/strong>
Zahidul Islam, Ilya Gurevic, Muhammad Saeed, Sobia Rasool, Amnon Kohen<\/em>
FASEB Journal, April 2017<\/em>
DOI: 10.1096\/fj.201601234R<\/strong>

42- <\/em>Synthesis of lignin model compound containing a \u03b2\u2011O\u20114 linkage<\/strong>
Asma Mukhtar, Muhammad Zaheer, Muhammad Saeed, Wolfgang Voelter<\/em>
Zeitschrift f\u00fcr Naturforschung B, February 1, 2017<\/em>Publications \u2013 2015
DOI: 10.1515\/znb-2016-0201<\/strong>

43- Resveratrol Prevents Estrogen\u2011DNA Adduct Formation and Neoplastic Transformation in MCF\u201110F Cells<\/strong>
Muhammad Saeed<\/em>
Cancer Prevention Research, September 18, 2015<\/em>
DOI: 10.1158\/1940-6207.CAPR-08-0037<\/strong>

44- <\/em>Targeting the de Novo Biosynthesis of Thymidylate for the Development of a PET Probe for Pancreatic Cancer Imaging<\/strong>
Thushani D Nilaweera, Muhammad Saeed, Amnon Kohen<\/em>
Biochemistry, February 10, 2015<\/em>Publications \u2013 2012
DOI: 10.1021\/bi501481n<\/strong>

45- A fast chemoenzymatic synthesis of [11C]\u2011N5,N10\u2011methylenetetrahydrofolate as a potential PET tracer for proliferating cells<\/strong>
Muhammad Saeed, Timothy J Tewson, Colbin E Erdahl, Amnon Kohen<\/em>
Nuclear Medicine and Biology, July 15, 2012<\/em>
DOI: 10.1016\/j.nucmedbio.2011.12.003<\/strong>

46- <\/em>Effect of tumour necrosis factor\u2011alpha on estrogen metabolic pathways in breast cancer cells<\/strong>
Marwa Kamel, Samia Shouman, Mahmoud El\u2011Merzebany, Gokhan Kilic, Timothy Veenstra, Muhammad Saeed, Mohamed Wagih, Concepcion Diaz\u2011Arrastia, Deepa Patel, Salama Salama<\/em>
Journal of Cancer, July 6, 2012<\/em>
DOI: 10.7150\/jca.4584<\/strong>

47- <\/em>Mechanism of DNA depurination by carcinogens in relation to cancer initiation<\/strong>
Ercole Cavalieri, Muhammad Saeed, Muhammad Zahid, David Cassada, Daniel Snow, Momcilo Miljkovic, Eleanor Rogan<\/em>
IUBMB Life, February 2012<\/em>Publications \u2013 2011
DOI: 10.1002\/iub.586<\/strong>

48- Formation of dopamine quinone\u2011DNA adducts and their potential role in the etiology of Parkinson\u2019s disease<\/strong>
Muhammad Zahid, Muhammad Saeed, Li Yang, Cheryl Beseler, Eleanor Rogan, Ercole L Cavalieri<\/em>
IUBMB Life, December 2011<\/em>
DOI: 10.1002\/iub.538<\/strong>

49- <\/em>Formation of diethylstilbestrol\u2013DNA adducts in human breast epithelial cells and inhibition by resveratrol<\/strong>
Benjamin Hinrichs, Muhammad Zahid, Muhammad Saeed, Mohammed F Ali, Ercole L Cavalieri, Eleanor G Rogan<\/em>
Journal of Steroid Biochemistry and Molecular Biology, November 1, 2011<\/em>
DOI: 10.1016\/j.jsbmb.2011.08.009<\/strong>

50-<\/em>Novel positron emission tomography tracer distinguishes normal from cancerous cells<\/strong>
Muhammad Saeed, David Sheff, Amnon Kohen<\/em>
Journal of Biological Chemistry, September 30, 2011<\/em>
DOI: 10.1074\/jbc.M111.275446<\/strong>

51-<\/em>The effect of tamoxifen and raloxifene on estrogen metabolism and endometrial cancer risk<\/strong>
Marian Y Williams\u2011Brown, Sana M Salih, Xia Xu, Timothy D Veenstra, Muhammad Saeed, Shaleen K Theiler, Concepcion R Diaz\u2011Arrastia, Salama A Salama<\/em>
Journal of Steroid Biochemistry and Molecular Biology, September 1, 2011<\/em>Publications \u2013 2010
DOI: 10.1016\/j.jsbmb.2011.05.001<\/strong>


52-N\u2011acetylcysteine blocks formation of cancer\u2011initiating estrogen\u2013DNA adducts in cells<\/strong>
Muhammad Zahid, Muhammad Saeed, Mohammed F Ali, Eleanor G Rogan, Ercole L Cavalieri<\/em>
Free Radical Biology and Medicine, March 2010<\/em>
DOI: 10.1016\/j.freeradbiomed.2010.04.028<\/strong>

53-<\/em>Benzene and dopamine catechol quinones could initiate cancer or neurogenic disease<\/strong>
Muhammad Zahid, Muhammad Saeed, Eleanor G Rogan, Ercole L Cavalieri<\/em>
Free Radical Biology and Medicine, February 2010<\/em>
DOI: 10.1016\/j.freeradbiomed.2009.11.002<\/strong>
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what we do<\/h3>\t\t\t\t<\/div>\n\t\t\t\t
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The Bioorganic & Medicinal Chemistry (BMC) group focuses on advancing research in organic synthesis, medicinal chemistry, and drug discovery. Our work spans from designing new molecules and polymers to interpreting NMR spectra and exploring innovative approaches in chemical education. We combine laboratory research with computational tools and science communication to train the next generation of chemists and contribute to solving real\u2011world challenges.<\/p>\t\t\t\t<\/div>\n\t\t\t\t

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Research Expertise <\/h2> <\/div>\n

Advancing synthetic organic chemistry, medicinal chemistry, and drug discovery.<\/p><\/div> <\/div>\n <\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Student Training<\/h2> <\/div>\n

Guiding undergrad and graduate students in synthesis, computational design, and lab skills<\/p><\/div> <\/div>\n <\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Collaborations <\/h2> <\/div>\n

Working with academia and industry to develop smart therapeutic solutions.<\/p><\/div> <\/div>\n <\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Publications & Outreach <\/h2> <\/div>\n

Sharing discoveries through journals, conferences, and science communication.<\/p><\/div> <\/div>\n <\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t

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Welcome to the Bioorganic & Medicinal Chemistry (BMC) Group<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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The BMC group is dedicated to advancing science at the interface of chemistry and biology. We design and synthesize novel organic molecules, apply computational chemistry and molecular modeling, and evaluate biological activity to discover new therapeutic agents and smart drug delivery platforms. Our mission is to bridge fundamental chemistry with translational biomedical research, creating solutions for cancer, viral diseases, and beyond.<\/p>\t\t\t\t<\/div>\n\t\t\t\t

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Our research spans anticancer and antiviral drug discovery, endocrine\u2011resistant breast cancer, peptide\u2011based nanomaterials, stimuli\u2011responsive drug delivery systems, and sustainable catalytic technologies. By aligning creativity with rigorous science, we aim to transform challenges into opportunities for innovation. We believe that the future of medicine lies in interdisciplinary collaboration, and we are committed to training the next generation of scientists to lead this transformation.<\/p>\t\t\t\t<\/div>\n\t\t\t\t

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\u201cWhere molecules meet medicine, innovation begins.\u201d \u2013 BMC Group Vision<\/p>\t\t\t\t<\/div>\n\t\t\t\t

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We envision a world where chemistry empowers health, discovery fuels progress, and collaboration drives breakthroughs.<\/p>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

About Us The Bioorganic & Medicinal Chemistry (BMC) group is committed to advancing science at the interface of chemistry and biology. Our research focuses on organic synthesis, computational chemistry, molecular modeling, and biological evaluation to discover new therapeutic agents and smart drug delivery platforms. We explore areas such as anticancer and antiviral drug discovery, endocrine\u2011resistant […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_eb_attr":"","footnotes":""},"class_list":["post-55","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/medchem.lums.edu.pk\/index.php?rest_route=\/wp\/v2\/pages\/55","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medchem.lums.edu.pk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/medchem.lums.edu.pk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/medchem.lums.edu.pk\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/medchem.lums.edu.pk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=55"}],"version-history":[{"count":87,"href":"https:\/\/medchem.lums.edu.pk\/index.php?rest_route=\/wp\/v2\/pages\/55\/revisions"}],"predecessor-version":[{"id":622,"href":"https:\/\/medchem.lums.edu.pk\/index.php?rest_route=\/wp\/v2\/pages\/55\/revisions\/622"}],"wp:attachment":[{"href":"https:\/\/medchem.lums.edu.pk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=55"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}